National Academy of Neuqwychology
Ward, J., ROSS, L. K., & Long, C. J. University of Tennessee - Nemphis State University Neuropsychology Laboratory Behavioral and cognitive changes after posterior hypothalamotomy Surgical lesioning of the posterior hypothalamus has been employed to modify severe emotional disorders. This study presents five case histories of patients treated for severe aggressive, hostile, and impulsive behaviors by posterior hypothalamotomy. In addition to describing postsurgical behavioral changes, the specific pre-surgical manifestations of each patient's symptoms and the related social disruption are examined along with available psychometric data. Furthermore, presenting symptomotology which determined patients' surgical candicacy is considered. A neuroanatomical system is proposed, providing a rationale for posterior hypothalamic surgery and its expected effect on behavior. These diverse case histories indicate that a multiplicity of factors (e.g., environmental, social, initial diagnosis, previous treatment, neuroanatomical mechanisms, etc.) influences psychological outcome.
Warner, M.W.. Dodrill KS.,, and Batzel, L-W. Epilepsy Center, Universzty of Washington. Are People with Complex Par-t%al Cieizureei More PoorI v ‘,y g:) <:! c;‘::I Ad.juated than Penple with otherCleizure The MMPI and the Washington Fsvcrhosoc i al Seizure Inventor-y !WF'SI) were adminizstered to 2’7Y adults with seizures (57 complex partial only? &7 generaliked convulsive only, 133 with both complex partial and generalized convulsive aeizrures). Indivxduals with only complex partial seizures general 1 y praduced pro+1 les th;:il. were very similar to those with only generalized convulT.!.'d!.:. eeizures. In contrast, people with with two seizure typehad higher elevations on four MMPI (i-k,D, HY, Ma) and +C.IQ~ WPSI (Emotional Adjustment, Vocational Adjustment, Adjustment to Seizures, Overall Psychosocial FunctlOningj clinical scales, and lower Lie scales on both inventories. When group differences were found in three-group comparisons, those with two seirure types generally had higher profile8 than those with only one seizure type. This study sugge&a that the type of epilepsy (temporal lobe vs. generalized) eg!r_se is a less important factor in. emotional and psychosocial functioning than the number- of seizure [email protected]
Although results in this study were statistically significant, we feel that seizure type is a relatively weak factor and that differences found in jnventory profiles are not terribly significant clinically. This investigation was supported by the Epilepsy Foundation o+ America and the NINCDS INS17111 P, NS24823).