BOOK REVIEWS 4. Schnitzer B: Reactive lymphoid hyperplasia in surgical pathology of the lvmph nodes and related organs, in laffe ES (ed): Maior Problems in Pathblogy Series, Vol 16. Philadiphia, S&mders, 1985, p 46 5. Harris NL, Bhan AK: Mantle-zone lymphoma. A pattern produced by lymphomas of more than one cell type. Am J Surg Pathol9:872-882, 1985 6. Azzopardi JC: Oat cell carcinoma of the bronchus. J Pathol Bacterial 78:513-519, 1959 7. Pileri S, Kikuchi M, Helbron D, et al: Histiocytic necrotizing lymphadenitis without granulocytic infiltration. Virchows Arch [A] 395:257271. 1982 8. Dorfman RF: Histiocytic necrotizing lymphadenitis of Kikuchi and Fuiimoto. Arch Pathol Lab Med 111:1026-1029, 1987 9. Turner RR, Martin J, Dorfman RF: Necrotizing lymphadenitis. A study of 30 cases. Am J Surg Pathol 7:115-123, 1983 10. Carbone A, Manconi R, Volpe R, et al: Enzyme- and immunohistochemical study of a case of histiocytic necrotizing lymphadenitis. Virchows Arch [A] 408:637-647, 1986 11. Unger PD, Rappaport KM, Strauchen JA: Necrotizing lymphadenitis (Kikuchi’s disease). Report of four cases of an unusual pseudolymphomatous lesion and immunologic marker studies. Arch Pathol Lab Med 111:1031-1034, 1987
are probably not helpful in distinguishing lupus lymphadenitis from histiocytic necrotizing lymphadenitis of Kikuchi and Fujimoto for cases in which the histologic findings are not diagnostic. Whether the indistinguishable immunohistologic results may also reflect similarities in the pathogenesis of these two disorders or are merely indicative of necrosis occurring in lymph nodes secondary to any lymphoid process is not known. REFERENCES 1. Fox RA, Rosahn PD: The lymph nodes in disseminated lupus erythematosus. Am J Pathol 19:73-79, 1943 2. Ginzler AM, Fox TT: Disseminated lupus erythematosus: A cutaneous manifestation of a systemic disease (Libman-Sacks). Report of a case. Arch Intern Med 65:26-50, 1940 3. Klemperer P, Gueft B, Lee SL, et al: Cytochemical changes of acute lupus erythematosus. Arch Pathol Lab Med 49:503-516, 1950
tion, while the obstetrician is scolded for the failure to deliver tissue in a timely fashion to the pathologist. General pathologists will find several practical items stressed in this text. These include anatomic rules of thumb, pertinent embryologic diagrams, checklists for external exams, and hints on approaches to gross photogra-
The Malformed Fetus and Stillbirth-A Diagnostic Ap preach. RM Winter, SAS Knowles, FR Bieber, et al. Chichester, NY, Wiley, 1988, 3 17 pages, $115.50. This book represents a significant departure from many available texts dealing with fetal and perinatal disease. First, it is not a multi-authored compendium with designated editor(s), nor is it an encyclopedic tome which intimidates the novice reader. The stated intent of this book is, in fact, to provide an easy to use text that offers a systematic approach to the evaluation and study of maldevelopment in the embryo, fetus, stillborn, and deceased newborn. The authors of this book largely succeed at their stated task. They emphasize a multidisciplinary approach to the study of fetal and perinatal disease that encompasses geneticists, pathologists, pediatricians, radiologists, and obstetricians. Moreover, the backgrounds of the authors support this approach-two are geneticists and two are pathologists. The book is well-organized, with an outline that is stressed in the initial chapters along with careful definitions of terms. The text is generally well-written, with succinct short chapters. Each chapter is followed by its own pertinent references. The pathologist reading this book will receive an immediate sense of his or her role in the evaluation of the malformed fetus and stillbirth. The authors note that properly organized and systematic study of such cases is sadly lacking in all but a few medical centers. It is clear from the design of this book that the volume is intended to alleviate some of the problems inherent in such studies. The book is both morphologically and problem oriented. It discusses the differential diagnosis of malformations, starting with the lesions themselves at various body sites or in organ systems. It stresses the need for, and limitation of, chromosomal analysis, specimen radiographs, and placental examinations. The book provides well-designed tables correlating morphologic abnormalities with diagnostic syndromes or karyotypic abnormalities; it also provides tables of normal reference values. Most importantly, the information is not presented in a clinical vacuum; the roles of the radiologist, geneticist, and obstetrician are also discussed with regard to evaluation of the malformations. The histopathologist is sometimes berated for the lack of thorough dissec-
PhY. The one drawback of this book is the quality of some of its reproductions. While the gross photographs are numerous and excellent, photomicrographs are few in number, sometimes poorly marked, or simply lacking in designations. Diagrams reproduced from other references are occasionally too small or have poor contrast. The overall evaluation of this volume on malformations is a strongly positive one. The authors have sensed a need for the description of a methodologic approach to the autopsy of the malformed fetus and stillbirth. The resultant book describes a thorough, yet pragmatic, approach to such autopsies in a problem-oriented fashion. While this work has appeal to multiple medical disciplines, its design and content are especially applicable to any pathologist working in neonatal, perinatal, or fetal problem areaS.-STEPHEN J. QUALMAN, MD, Assistant Professor of Pathology, Ohio State University, and Staff Pathologist, Children’s Hospital, Columbus, OH Color Atlas and Textbook of Diagnostic Parasitology. Tsieh Sun. New York, Igaku-Shoin, 1988, 317 pages, $85 As stated in the introduction, this book is meant to be a practical handbook to guide persons who work in parasitology and related fields in achieving a diagnosis on the basis of clinical information and examination of the specimens. The author has indeed accomplished his avowed task. The book is divided into 49 chapters and a technical appendix, covering all common and uncommon parasites known to infest man. Each chapter is composed of a textbook portion, which reviews in a few pages the pertinent facts concerning the epidemiologic, parasitologic, clinical, and pathologic features of the organism, followed by several illustrations and the atlas portion, which are reproduced mostly in color. Selected and up-to-date references are also included in each chapter. The technical appendix contains several useful and commonly used laboratory procedures and staining techniques.
Volume 20, No. 3 (March 1989)
The book is written in a clear, concise manner. The style is dark, headings are bold, and the paper is of excellent quality. Most of the illustrations are first class quality. The result is, as one expects, a nicely presentable book that is a pleasure to consult. However, some minor deficiencies are noted. First, the author had to use several photographs of museum pieces in glass jars appearing with a dull, dirt-brown color, rendering the identification of characteristic lesions rather difficult (Figs 9-l and 38-5). This is probably due to the lack of first-hand, fresh materials which are hard to find in this country. A few pictures appear to be out of focus (Figs 38-9 and 42-6). Several microphotographs of H&E sections are poor-quality, a painful fact for pathologists (Figs 15-33 and 28-6). Figure 7-2 illustrates the presence of axostyle in trophozoites of Giardia lamblia. This structure is now regarded by many authors as axoneme and not true axostyle. Figure 11-5, of cryptosporidium oocysts, was taken with a magnification too low to be of help. Not all acid-fast bodies in the stools are ooccysts and the presence of internal structures is often required for definite identification. Despite these few minor deficiencies, this Color Atlas and Textbook is a valuable and indispensable reference book, and deserves a special place among the shelves of every microbiology department.-ANH DAO, MD, Metro Nashville General Hospital; Nashville. TN. Immunology: Basic Concepts, Diseases, and Laboratory Methods. J. Helen Cronenberger, J Charles Jenette. Norwalk, CT, Appleton and Lange, 287 pages, $26.95. Immunology tial applications
is a rapidly expanding field, with potenin every facet of anatomic or clinical pa-
NOTICES Symposium: Third Annual Medical College of Georgia Postgraduate Pathology Symposium Major Topic: The Differential Diagnosis of Pigmented Lesions of the Skin April 22-23, 1989 Forfurther information, contact William C. Allsbrook, Jr, MD, Department of Pathology, Medical College of Georgia, Augusta, GA 30912-0300; (404)72 l-2594. Meeting: Twentieth Annual Continuing Medical Education Meeting of the New York StateSociety of Pathologists Update on Breast, Gynecologic, and Pediatric Pathology Cytology and Immunoperoxidase April 28-30, 1989 For further information, contact Nathan Taylor, MD, Rochester General Hospital, Rochester, NY 1462 1; (7 16)338-412 1, or Terry Knudsen, New York State Society of Pathologists; (914)687-0955.
thology. New laboratory methods derived from these advances include immunofluorescence microscopy, latex particle agglutination, radioimmunoassays, enzyme immunoassays, immunoprecipitations, and immunohistochemistry, to name only a few. While these rapid advances have facilitated clinical laboratory medicine, the new methodology and nomenclature challenge our abilities to remain informed. For the sophisticated immunologist seeking detailed, up-to-date information, this text will be disappointing. However, for teaching immunology and immunopathology to technicians, medical students, or inexperienced pathologists, it has some merit. Chapters 1 through 4 introduce and review the immune system, non-immune defenses, and basic laboratory methods. Chapters 2, 6, and 7 describe lymphocytes and lymphoid tissues, immunodeficiency syndromes and their diagnoses, leukemias, and lymphomas; this section might be a tedious review for fully trained physicians. The lymphoma section is presented using the National Cancer Institute Working Formulation and the Rappaport classification systems. Lymphoid markers are briefly discussed, but immunohistochemical methods or pitfalls of interpretation are not presented. Chapters 8, 9, 10, and 11 review immune responses and immune-mediated diseases. The final two chapters summarize immunology and serology of infectious diseases. Photomicrographs and photographic illustrations are of moderate quality but usually convey the necessary information. Illustrations and illustrative clinical cases maintain reader interest. This text will be most useful for the pathologist responsible for educational programs in immunology or clinical laboratory medicine.-ANN D. THOR, MD, Assi.tant Professor of Pathology, Haroard Medical School, Boston.
Course: “Newer Techniques in Diagnostic Pathology” Twenty-Ninth Annual Meeting of the Houston Society of Clinical Pathologists April 29, 1989 For further information, contact Tamara C. Greiner, Program Coordinator, The Office of Continuing Education, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030; (713)798-6020.
Course: Third Annual “Advances in Surgical Pathology” Postgraduate Course Washington, DC, May 19-20, 1989 For further information, contact Dr Steven Silverberg (202)994-8823, or the Continuing Medical Education Office, The George Washington University, Washington, DC, 20037; (202)994-4285.