Corrigendum to “3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-xL and Mcl-1” [Bioorg. Med. Chem. 21 (2013) 11–20]

Corrigendum to “3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-xL and Mcl-1” [Bioorg. Med. Chem. 21 (2013) 11–20]

Bioorganic & Medicinal Chemistry 22 (2014) 663–664 Contents lists available at ScienceDirect Bioorganic & Medicinal Chemistry journal homepage: www...

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Bioorganic & Medicinal Chemistry 22 (2014) 663–664

Contents lists available at ScienceDirect

Bioorganic & Medicinal Chemistry journal homepage: www.elsevier.com/locate/bmc

Corrigendum

Corrigendum to ‘‘3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-xL and Mcl-1’’ [Bioorg. Med. Chem. 21 (2013) 11–20] Ting Song a, , Xiangqian Li a, , Ying Yang b, Guiye Wu a, Shenghui Xie a, Pengchen Su a, Yingang Feng c,⇑, Zhichao Zhang a,⇑ a b c

State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, Dalian 116012, People’s Republic of China Public Laboratory of Bioenergy and Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, People’s Republic of China Shandong Provincial Key Laboratory of Energy Genetics, Qingdao Institute of Bioenergy and Bioprocess Technology, Qingdao 266101, People’s Republic of China

Page 16, In Scheme 1, the structures of 5a–k should be corrected as following: O

CN

H N

N

Correction

R

9

H N

O

R= CH 2CH3, CH2CH 2CH3, CH2(CH2) 2CH3, CH2(CH2)3CH 3, CH2(CH2) 4CH3, CH(CH3) 2, CH 2Ph, CH2(CH2) 2Ph, CH 2(CH 2)3Ph, CH2(CH 2) 4Ph, CH2(CH 2) 5Ph

R

3

6

3 N

N

S

S

incorrect structures in Bioorg. Med. Chem. 2013, 21

corrected structures

Page 13, 14, In Tables 1 and 2, the structures of 6a–d, 7a–d should be corrected as following: O N

H N

9

CN R2

Correction

H N

O

3

R2

R1 = NH 2, OCH3, CH(CH 3)2 CH2(CH 2) 2CH3, R2 = CH (CH ) CH 2 2 4 3 CH2(CH 2) 2Ph

6

3 S

S R1

incorrect structures in Bioorg. Med. Chem. 2013, 21

q

DOI of original article: http://dx.doi.org/10.1016/j.bmc.2012.11.008

R1

corrected structures

⇑ Corresponding authors. Tel./fax: +86 411 84986032 (Z. Zhang), tel.: +86 0532 80662706; fax: +86 0532 80662707 (Y. Feng).  

E-mail address: [email protected] (Z. Zhang). These authors contributed equally to this work.

0968-0896/$ - see front matter Ó 2013 Elsevier Ltd. All rights reserved. http://dx.doi.org/10.1016/j.bmc.2013.10.043

664

T. Song et al. / Bioorg. Med. Chem. 22 (2014) 663–664

Page 16, In Figure 4, Figure 4c should be corrected as following:

Correcon p4 p4 R263

R263

Page S16 of Supplementary data, in line 12, ‘‘calcd for 349.4503, found 349.1205’’ should be corrected to ‘‘calcd for 363.1426, found 363.1431’’. Page S17 of Supplementary data, in line 22, ‘‘calcd for 377.1562, found 377.1565’’ should be corrected to ‘‘calcd for 363.1405, found 363.1409’’.