Erythema Multiforme in an Alcoholic Patient

Erythema Multiforme in an Alcoholic Patient


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OOOO Volume 120, Number 2 PCC-065 - MORPHOLOGICAL CHANGES IN THE TEMPOROMANDIBULAR JOINT AFTER FACIAL TRAUMA: A CASE REPORT. TALITA ARRAIS DANIEL MENDES, ALAIN OLIVEIRA DOS SANTOS, DELANE VIANA GONDIM, HELLÍADA VASCONCELOS CHAVES, ALYNNE VIEIRA DE MENEZES PIMENTA, LÚCIO MITSUO KURITA, FÁBIO WILDSON GURGEL COSTA. UNIVERSIDADE FEDERAL DO CEARÁ. The temporomandibular joint (TMJ) has its peculiarities in terms of movement, anatomy, and ordered interactions. Facial trauma can result in adaptive modifications of the TMJ. Here, we report a case of anatomical changes in the TMJ following a facial fracture in a 22-year-old patient. The patient had suffered a right condylar fracture in an automobile accident at the age of 9 years. At that time, the fracture was treated with physiotherapy. Thirteen years later, magnetic resonance imaging showed morphological changes in the right condyle and articular disc; there was sagittal plane deformity of the condyle, with no involvement of the articular fossa. Fracture of the condyle during development can have various consequences, including painful, disabling conditions that can cause condylar hypoplasia or anatomical deformities.

PCC-066 - ERYTHEMA MULTIFORME IN AN ALCOHOLIC PATIENT. SAMANTHA CARDOSO DE ANDRADE, ADRIANA MACHADO ZARZAR, EUCAÉ MIRANDA MISSIAS, LUIZ ALCINO MONTEIRO GUEIROS, ALESSANDRA DE ALBUQUERQUE TAVARES CARVALHO, JAIR CARNEIRO LEÃO. UNIVERSIDADE FEDERAL DE PERNAMBUCO. Erythema multiforme (EM) is a type of hypersensitivity reaction. It typically occurs in response to drugs, infections, or any one of a variety of diseases. To our knowledge, EM after heavy alcohol consumption has been reported only rarely. A 33-year-old male presented with a 2-week history of extensive ulceration of the oral mucosa, pain, and inability to eat. The patient denied illicit or recreational drug use but mentioned a long history of alcoholic intake. The results of a physical examination and routine laboratory tests were normal. Histopathological examination revealed epidermal necrosis with individual dyskeratotic keratinocytes, together with perivascular lymphocytic infiltration. Intraoral examination showed extensive, irregular ulceration, with sloughing, on the tongue and lower lip. On the basis of the clinical and laboratory features, we established a diagnosis of EM, possibly associated with heavy alcohol consumption.

PCC-067 - ORAL POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDERS AFTER KIDNEY TRANSPLANTATION. ANA CAROLINA AMORIM PELLICIOLI, ALINE ALVES LUCIANO, ANA LÚCIA CARRINHO AYROZA RANGEL, GREISON RABELO DE OLIVEIRA, OSLEI PAES DE ALMEIDA, PABLO AGUSTIN VARGAS. FACULDADE DE ODONTOLOGIA DE PIRACICABA e UNICAMP. Post-transplant lymphoproliferative disorders (PTLDs) comprise a spectrum of complications that affect immunocompromised patients following hematopoietic stem cell transplantation or solid organ transplantation. Its incidence varies according to the transplanted organ occurring in approximately 2.3% of kidney transplants. A 31-year-old female was referred to a dental clinic for evaluation of an oral lesion. Her medical history included kidney transplantation,

ABSTRACTS Abstracts e37 and she was under standard immunosuppression therapy. Intraoral examination revealed osteonecrosis in the gingiva of the right posterior mandible. Teeth were extracted, and an incisional biopsy was performed. Histological examination showed small hyperchromatic neoplastic cells and pale nuclei showing prominent nucleoli permeating connective tissue, muscle fibers, and adipocytes. Immunohistochemical analysis was carried out for CD3, CD10, CD20, CD30, CD79a, and MUM1, as was in situ hybridization for EBV. Based on the clinical, histological, and immunohistochemical findings, the final diagnosis was PTLD composed of B and T cells, associated with EBV.

PCC-068 - PEMPHIGUS VULGARIS: A CASE REPORT. THAYSE GONZAGA GOMES, SANDRA APARECIDA MARINHO, GUSTAVO GOMES AGRIPINO, SÉRGIO HENRIQUE GONÇALVES DE CARVALHO, ROBÉRIA LÚCIA DE QUEIROZ FIGUEIREDO, DMITRY JOSÉ DE SANTANA SARMENTO. UNIVERSIDADE ESTADUAL DA PARAÍBA. Pemphigus vulgaris is a chronic vesiculobullous skin disorder. A 48-year-old Black female sought treatment at a stomatology clinic because of multiple lesions on the oral mucosa. In anamnesis, she reported prior medical examination and antibiotic use. Extraoral examination revealed ulcers and crusts in the throat, eyes, and nose, sometimes with bleeding; the patient reported similar lesions in her armpits and vagina. The intraoral clinical findings were ulceration, drooling, halitosis, and blisters that were easily ruptured. The diagnosis of pemphigus vulgaris was based on clinical features and a positive Nikolsky sign. The histopathological examination of intraoral lesions demonstrated intraepithelial blister with some acantholytic cells; the basal cells were separated from one another in a “tombstone” pattern. Recognition of the clinical picture of this disease is important for effective therapeutic targeting in order to prevent progression of the disease and its comorbidities.

PCC-069 - PSORIASIS: A RARE CASE OF INTRAORAL LESIONS. CAROLINE ZIMMERMANN, MARIA INÊS MEURER, ELENA RIET CORREA RIVERO, AIRA MARIA BONFIM SANTOS, MONIQUE CUNHA DA SILVA, LILIANE JANETE GRANDO. UNIVERSIDADE FEDERAL DE SANTA CATARINA. Psoriasis is a chronic dermatosis characterized by increased proliferation of skin keratinocytes. The lesions appear as erythematous, typically symmetrical, desquamative plaques that can be pruritic. Oral lesions are rare and can appear as red and white plaques or as ulcers. An adult male, previously diagnosed with cutaneous psoriasis, presented with lesions resembling burns on the soft palate; he also reported a 4-month history of xerostomia and metformin use. Intraoral examination revealed areas of erosion interspersed with desquamative areas in the soft and hard palate, uvula, and isthmus of the fauces, with a 2mm ulcer at the left lingual base. Laboratory tests showed a fasting glucose level of 172 mg/dl. A solution of 0.1% clobetasol propionate’s and 100,000 IU of nystatin was prescribed for mouthwash and gargling 3/day. The oral lesions were treated with low-level laser therapy and the patient was referred for homeopathy and endocrinology consultations. The oral lesions improved after treatment. The patient remains under follow-up.