Glanders tested by mallein. An anomalous case

Glanders tested by mallein. An anomalous case

CLINICAL ARTICLES. Post-1Il0rtelll.- The peritoneal cavity contained 3 pints and 3 ozs. of a fluid which, as regards its naked-eye appearance, was ab...

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CLINICAL ARTICLES.

Post-1Il0rtelll.- The peritoneal cavity contained 3 pints and 3 ozs. of a fluid which, as regards its naked-eye appearance, was absolutely indistinguishable from ordinary milk. It had no tinge of redness, and contained no clots. The lacteals in the lower part of the mesentery were visible from the chyle in them. No rupture or abnormality could be detected in connection with them. The thoracic duct was easily found over the base of the heart and followed back to the receptaculum chyli; it contained a small quantity of faint-pink lymph, and appeared to be quite intact, as was also the receptaculum. The blood-vessels of the omentum and mesentery were much congested, those of the rest of the peritoneum less so. The liver was fatty, and the other organs were normal. Professor M'Fadyean, who examined the peritoneal fluid, reported that it showed under the microscope an appearance identical with that of normal chyle, its opacity and whiteness being apparently due to the very minute fatty particles suspended in it. It contained no epithelium, and yielded neither sediment nor cream when subjected to the action of the centrifugal machine. ~~~~------

GLANDERS TESTED BY MALLEIN.

AN ANOMALOUS

CASE.

By H. W. CATON, F.R.C.V.S., London. THE subject of this note was a bay mare which was known to have been exposed to the contagion of glanders, but which showed no symptom whatever indicating that she had contracted the disease. I injected her with mallein on the 25th of February last at 4 P.M. with the following result:~ Hottr.

Temp.

Local Reaction. "----

4.0 p.m.

lO~·S

S.o p.m.

101'Z

IZ.O p.m.

loz'4

4.0 a.m.

104'2

S.o a.m.

10.-1-"2

-

-

} Moot "ten,i" ,w'lling (. 5 in. , 9 in.) at seat of injection.

As a result of this test it was concluded that the mare was glandered, but the owner was reluctant to have her killed, and she was therefore isolated. In the month of August it was decided to test the mare again, and for this purpose she was sent to the Veterinary College, where she was injected with mallein by Professor Axe. Unfortunately I have not the exact record of the temperature, but on this occasion there was neither local nor general reaction. The isolation of the mare was still maintained, and on the 14th of December last she was again sent to the Veterinary College, where

377

ABSTRACTS.

she received a third injection with mallein, with the result shown below. Hour.

Local Reaction.

Temp.

7.0

p.m.

IO~·S

1.0

a.m.

100'2

4.0

a.m.

100'6

7.0

a.m.

100'S

10.0

a.m,

101'2

1.0

p.m.

101'0

(Injected.)

Swelling at seat of injection insignicant.

I t ought here to be stated that the mare had not yet developed any sign of glanders or farcy, and she remained throughout in excellent condition. Notwithstanding this the owner was persuaded to have the mare killed. This was done on the 15th of December, and the post-mortem revealed about half a score of glanders tubercles in the lungs, most of them small and some gritty. QuerJI.- \Vas this a case of failure of mallein, or a case of arrested glanders?

PROTECTIVE INOCULATION AGAINST SWINE ERYSIPELAS. LORENZ (Cmtralbl. f Bakt., Band xiii, Nos. I I and 12) observes that Pasteur's method of protective inoculation against swine erysipelas (injection of artificially attenuated culture of rtJ.e bacillus) cannot be regarded as satisfactory, since many of the inoculated animals succumb. Lorenz himself describes an improved method which he has introduced, and which consists in inoculating the swine with serum of rabbits or swine which, having been rendered immune to swine erysipelas by an attack of that disease, or artificially, have thereafter been injected with gradually increasing doses of virulent culture of the specific baCillus. The author has been able to prepare from the protective serum a fluid which contains the dctive principles, and has thus largely removed the inconvenience which the injection of a considerable bulk of fluid entails. The method of preparation is not published. at present.Brit. .3fed. Journal.

COLOCYNTHIN AS A

PURGATIVE FOR THE DOG.

As the result of experiments made 0n dogs Baum draws the following conclusions regarding the action of Colocynth. T. Pure colocynth in when administered by rectal injection in combination with alcohol and glycerine is a powerful purgative for the dog.