Volume ..... No.3 DEATH IN STATUS ASTHMATICUS September 1963 SUMMARY AND CONCLUSIONS Thirty patients with status asthmaticus were studied and divi...

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Volume ..... No.3


September 1963


Thirty patients with status asthmaticus were studied and divided into two groups based on survival. The sedative medication received by those patients who survived and those who succumbed was compared. In those patients who died and in whom the amount of sedation received prior to death was known, there existed a high degree of correlation between death and the amount of sedation received. Although the two groups may not be strictly comparable, it seems clear that the more sedation that was given, the greater the hazard to life. RESUMEN

Se estudiaron 30 enfermos con estado de mal asmatico y se dividieron en dos grupos, basandose en la sobrevida. La medicaci6n sedante que recibieron los enfermos que sobrevivieron y los que fallecieron se compar6. En los que fallecieron y en los que la cantidad de sedantes se conoda antes de la muerte existfan una elevada correlaci6n entre la muerte y la cantidad de sedante administrado. Aunque los dos grupos no sean estrictamente com parables parece claro a mayor sedaci6n mayor peligro para la vida.

hatten, die am Leben blieben, wurde mit derjenigen verglichen, die bei den tOdlich ablaufenden Formen angewandt worden waren. Es erwies sich nun ein hoher Grad von Korrelation zwischen todlichem Ablauf und Ausma13 der vergenommenen Sedierung bei denjenigen Fallen, die zum Tode kamen und bei denen das Ausma13 der Sedierung vor dem Tode bekannt war. Obwohl beide Gruppen nicht im genauen Wortsinn vergleichbar sind, Iiegt es doch nahe anzunehmen, da13, je stlirker man sedierend vorgeht, umso groiler die Lebensgefahr ist.

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Trente malades atteints d'asthme furent ~tudi& et di~s en deux groupes selon leur survie. L'auteur a compare la medication ~dative recue par les malades qui survecurent et celIe recue par ceux qui succomberent, Chez ceux qui moururent et chez lesquels la quantite de s~datif recu avant la mort ~tait connue, il y avait un haut degr~ de correlation entre la mort et la quantite de sMatif recu, Bien que les deux groupes ne soient pas strictement comparables, il semble clair que plus la dose de ~datif donnee est ~Iev~e, plus Ie danger s'accroit.




Es wurden 30 Patienten mit einem Status asthmaticus untersucht und auf der Basis der 'Oberlebenszeit in zwei Gruppen geteilt. Die sedative Medikation, die diejenigen Patienten erhalten


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REFERENCES LEWIS, R. F. AND CLEVE, E. A. : "A Study of Relationships Between Meteorolo~c Variables and Asthma Admission to Chanty Emergency Center, New Orleans, Louisiana," Meteorologic Aspects of New Orleans Asthma. HAMILL, P. V.: "Air Pollution and Chest Disease," Dis. Chest, 39:477, 1961. UNOER, L.: "Pathology of Bronchial Asthma with Five Autopsy Reports," Southern Med. I ., 38 :513, 1945. BULLEN, S. S., SR. : "Correlation of Clinical and Autopsy Findings in 176 Cases of Asthma," I . Allergy, 23: 193, 1952. WALZER, I. AND FROST, T. T .: "Death Occurring in Bronchial Asthma, A Report of Five Cases," I . Allergy, 23: 204, 1952. CARDELL, B. S. AND PEARSON, R. S.: "Death in Asthmatics," Thorax, 14:341, 1959. EARLE, B. V.: "Fatal Bronchial Asthma, A Series of 15 Cases with a Review of the Literature," Thorax, 8 : 195, 1953. DRILL, V. A. ed: Pharmacology in Medicine, 2nd ed., McGraw-Hill, New York, 1958. BARACH, A. L. in : Symposium on Inhalation Therapy: "Treatment of Anoxia in Clinical Medicine," Bull. New York Acad. Med., 26 : 370, 1950. GOODMAN, L. S. AND GILMAN, A. : The Pharmacological Basis of Therapeutics, 2nd ed ., Macmillan , New York, 1955. BRESNICK, E., WOODARD, W. K. AND SAOEMAN, C. B. : "Fatal Reactions to Intravenous Administration of Aminophylline, Report of 3 Cases," J,A.M.A ., 136:397, 1948. MERRILL, G. A.: "Aminophylline Deaths," I .A.M.A., 123:1115, 1943. HILDlNO, A. C.: "Role of Ciliary Action in Production of Pulmonary Atelectasis, Vacuum in Paranasal Sinuses, and in Otitis Media," Ann. Otol . Rhin , and Laryng., 52 :816 , 1943.

For reprints, please write Dr . V. J. Deroo at 1430 Tulane Avenue, New Orleans 18, Louisiana.

PECTUS EXCAVATUM The optlmal age for operatlon b between three and Pectus excavatum b an uncommon deformity llve years. Subperlchondral strlpplng of all dewhose etlology Is not clear. The great maJorlty of formed rlb cartilages and rlb enda, removal of the patlents are without symptoms except for cosmetlc xlphold process, and osteotomy of the upper part aapects. In view of thls, surgical correctlon seldom of the sternum wIthout t1xatlon prostheses seem should be performed on women. It seems worthadequate. The results appear trratlfylng out of prowhlle to have the patlent undertake exercises to portlon to the skeletal correctlon obtained. promote the development of muscles and the expansion of lungs dUl'iq the perlod of observatlon. LYNN, H. B.: "Pectus Eu&,..tum, " T. Uaw, 83:106. 1963.