Tenth annual clinical nephrology meeting abstract April 17–22, 2001

Tenth annual clinical nephrology meeting abstract April 17–22, 2001

Tenth Annual Clinical Nephrology Meeting Abstracts April 17-22, 2001 Acute Renal Failure/ICU Medicine 81 Continuous Renal Replacement Therapy Using 2...

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Tenth Annual Clinical Nephrology Meeting Abstracts April 17-22, 2001 Acute Renal Failure/ICU Medicine 81

Continuous Renal Replacement Therapy Using 2% Trisodium Citrate Regional Anticoagulation in Liver Cirrhosis R. Smith, R. Campbell, P O'ReilIy, and A. Tolwani Division of Nephrology, University of Alabama, Birmingham, AL

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Hyperbaric-Oxygen Treatment: An Adjunctive Therapy in Acute Renal Failure Due to Crush Injury Rumeyza Kazancioglu, Cenk Gulgun, Salih Aktas, Mehmet S. Sever, Didem Korular, Seyit M. Kayacan, Nilgun Aysuna, Alaattin HIdiz, and Semra Bozfakioglu Istanbul Medical Faculty, Department of Internal Medicine, Division of Nephrology, and Department of Underwater Medicine, Istanbul, Turkey

38

Hypercoagulability in Dialysis Patients: Fact or Fiction? Andrea IannuzzelIi and Richard Kasama Kennedy Memorial Hospital, Stratford, NJ

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Management of Acute Renal Failure With On-line Haemodiafiltration Peter A. Rutherford and Ines Held University of Wales College of Medicine, Wrexham, UK

Diabetes 32

Cell Proliferation and Gene Expression in Cells From Diabetic (D) Patients (pts) Were Altered by Early Nonenzymatically Glycated Proteins C Huang, Y. Kim, M.L.A. Caramori, A.J. Fish, and M. Mauer University of Minnesota, Minneapolis, MN

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Long-Term Clinical Outcome Differences Between Nodular and Diffuse Mesangial Glomerulosclerosis in Type II Diabetic Nephropathy Marvin Sinsakul, Roger Rodby, Richard Rohde, and Edmund Lewis Collaborative Study Group, Rush Medical College, Chicago, IL

Electrolyte and Acid Base Abnormalities 48

Detection of Unsuspected Normal Pregnancy by the Abnormal Serum Chemistry Khanh vinh quoc Luong and Lan Thi Hoang Nguyen Vietnamese American Medical Research Foundation, Westminster, CA

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Evaluation of Risk of Cardiac Arrhythmias in Patients With Gitelman's Syndrome V. Weiss and TS. Ahuja University of Texas Medical Branch, Galveston, TX

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Functional Study of Cloned Renal Na+/HCO3 Cotransporters: Kinetics of Extracellular HCO3- Dependence and Interaction With SO3= Irina L Grichtchenko, Michael E Romero, and Walter E Boron Yale University, Department of Cellular and Molecular Physiology, New Haven, CT

11 Impaired Response to Chlorothiazide (CTZ) in Mice Lacking the Calcium (Ca) Channel/33 Subunit Josd F. Bernardo, W. Bruce Sneddon, and Peter A. Friedman University of Pittsburgh School of Medicine, Department of Medicine, Renal Electrolyte Division, and Department of Pharmacology, Pittsburgh, PA American Joumal of Kidney Diseases, Vo137, No 4 (April), 2001 : pp A1 -A36

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TENTH ANNUAL CLINICAL NEPHROLOGY MEETING ABSTRACTS

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Na+-Dependent C1-HCO3 Exchanger: Cloning, Tissue Distribution & Characterization Irina I. Grichtchenko, Inyeong Choi, John M. Russell, and Walter E Boron Yale University, Department of Cellular and Molecular Physiology, New Haven, CT, and Syracuse University, Department of Biology, Syracuse, NY

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Osteopontin Inhibits Calcium Oxalate Agglomeration in Postmenopausal Stone Formers K.M. Kellum, J.S. Lindberg, L.L. Hamm, F.E. Husserl, A.L. Burshell, D.J. [(ok, C. Westervelt, J.B. Copley, E. Reisin, and EE.C. Cole Ochsner Clinic, New Orleans, LA

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Proteins Can Reduce the Osmotic Water Permeability of Plasma Membranes Warren G. Hill, Marcia A. Kaetzel, Ge Zhou, Xiangpeng Kong, T.-T. Sun, John R. Dedman, and Mark L. Zeidel Renal Division, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, Department of Molecular and Cellular Physiology, University of Cincinnati, OH, and New York University School of Medicine, New York, NY

Glomerular Diseases 100

Acute Renal Failure Secondary to Renal Artery Embolism: A Case Report Sameer Yaseen Abdullah Alwahdani, and Victoria Lira University of Iowa, Department of lnternal Medicine, Iowa City, IA

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Anti-GBM Disease in Xenomouse II Is Induced by Human MAb Versus ~3(IV)NC1 Collagen K.E.C. Meyers, J. Allen, J. Gehret, M. Gallo, H. Hopfer, R. Kalluri, and MP Madaio University of Pennsylvania, Philadelphia, PA, Children's Hospital of Philadelphia, Philadelphia, PA, ABGEN1X, and Harvard University, Boston, MA

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Cytomegalovirus Associated Collapsing Glomerulopathy in a Non-Immunocompromised Host With No Risk Factors Indulekha Gopal, Saba Sile, LilIian Gaber, William Bastnagel, and Kunal Chaudharv Departments of Medicine and Pathology, University of Tennessee Health Sciences Center, Memphis, TN

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End-Stage Lupus Nephritis (ES-LN), Risk Factors for Coronary Heart Disease (CHD), and Echocardiographyc Study M. Milovanceva-Popovska, L. Grcevska, V. Ristovska, and M. Polenakovic Department of Nephrology, Medical Faculty, University of "Sts. Cyril and Methodius, " Skopje, Republic of Macedonia

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Fibrillary Glomerulonephritis and Necrotizing Glomerulonephritis in a Patient With Legionella Pneumonia Sameer Yaseen, Timothy Timmerman, and Christie P. Thomas Division of Nephrology, Department of lnternal Medicine, University of Iowa, Iowa City, 1A

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Immune Complex Glomemlonephritis in a Patient With Bartonella Henselae Endocarditis Gerardo A. Chica 111, Patrick D. Walker, Margie A. Scott, and Mary Jo Shaver Division of Nephrology, Division of Pathology, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock, AR

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MMP9/Gelatinase B Is Required for Neutrophil Infiltration in the Early Heterologous Phase of Anti-GBM Glomerulonephritis Jean-Phillipe Rougier, Karel Assmann, and Zena Werb Department of Anatomy, University of California, San Francisco, CA, Department of Pathology, Univerisity Hospital, Nijmegen, The Netherlands

TENTH ANNUAL CLINICAL NEPHROLOGY MEETING ABSTRACTS

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Prevalence of & Risk Factors for Renal Disease in a Population-Based Sample of HIV-Infected Patients L.vnda Szczech, Charles van der Horst, John Bartlett, and Laura Svetkey Duke University Medical Center, Durham, NC

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Successful Treatment of Steroid-Resistant Minimal Change Disease With Mycophenolate Mofetil Andrds Mogyordsi, H. Robert Lippman, and George M. Feldman VCU/Medical College of Virginia and McGuire VAMC, Richmond, VA

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Hemodialysis 39

A Malnutrition-Inflamation Score Is Correlated With Mortality in Maintenance Hemodialysis Patients Kamvar Kalantar-Zadeh, Joel D. KoppIe, Gladys Block, and Michael H. Humphreys Harbor-UCLA Medical Center, Torrance, CA, San Francisco General Hospital, San Francisco, CA, and UC Berkeley, School of Public Health, Berkeley, CA

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Bone Histomorphometry Is Still the Golden Standard for Diagnosing Renal Osteodystrophy Breda Pe(ovnik Balon, Radovan Hojs, and Andrej Bren Department of Nephrology, Maribor Teaching Hospital, Maribor, Slovenia, and Department of Nephrology, University Medical Center, LjubIjana, Slovenia

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Calciphylaxis Masquerading as Leukocytoclastic Vasculitis Richard K. Capling and Esther A. Gonzalez St. Louis University Health Science Center, St. Louis, MO

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Comparing Survival Across Dialysis Units--The Importance of a Rigorous Statistical Approach Peter A. Rutherford and Jo Charles University of Wales College of Medicine and North Wales Health Authority, Wrexham, UK

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Comparison of Two Protocols for Alteplase Administration in Occluded Tunnelled-Cuffed Hemodialysis Catheters M.J. Carvalho, J. Queirds, J. Santos, A. Cabrita, and S. Guimaraes Department of Nephrology, Hospital Geral de Santo Antdnio, Porto, Portugal

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Difficulties in Anemia Management of ESRD Dialysis Patients Iluminado Cruz, Lena Cauton, and Adrian Hosten Howard University Hospital, Washington, DC

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Do Angiotensin Converting Enzyme Inhibitors/Angiotensin Receptor Blockers Increase the Incidence of Hyperkalemia in Hemodialysis Patients? Asad Majid, Karthik Ranganna, Abbas Rabiei, Christie Roberson Scheier, Shoaib Chowdhury, Emily Huang, Kamran Hasni, Bulent Cuhaci, Jean Lee, and Ziauddin Ahmed MCP Hahnemann University Hospital, Philadelphia, PA

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Does Reuse of the Arterial Blood Tubing Segment Affect Dialyzer Blood Flow? M. Aslam, A. Besarab, and J. Zurbach West Virginia School of Medicine, Morgantown, WV Evidence-Based Support for NKF-DOQI Clinical Practice Guidelines for Vascular Access in Preventing Infections K.B. Stevenson, E.L. Hannah, C. Lowder, M.J. Adcox, R.L. Davidson, M.C. Mallea, N. Narsimhan, and J.P. WagniM PRO-West, Saint Alphonsus Nephrology Center, and Idaho Nephrology Associates, LLC, Boise, ID

TENTH ANNUAL CLINICAL NEPHROLOGY MEETING ABSTRACTS

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Hemodialysis Catheter-Related Intracardiac Thrombosis and Its Treatment With rtPA Adrian Ahmed, A.K. Salahudeen, and J.D. Bower University of MS Medical Center, Jackson, MS

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Hospitalization for Initiation of Hemodialysis Mario A. Martinez, A. Tejinder, Ahuja Agraharkar, and Mehendra Agraharkar University of Texas Medical Branch, Nephrology Division, Galveston, TX

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Hospitalizations for Pulmonary Embolism After Initiation of Chronic Dialysis in the United States Daniel P Tveit, Iman O. Hypolite, Ronald K. Poropatich, Paul I-Ishieh, David Cruess, Lawrence Y Agodoa, and Kevin C. Abbott Nephrology Service, Walter Reed Army Medical Center, Washington, DC, and Uniformed Services University of the Health Sciences, Bethesda, MD

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Influence of Nutrition on Serum Phosphorous, Calcium, and Calcium-Phosphorous Product (CCP) and Their Effects on Hemodialysis Survival AbduIla Salahudeen and John Bower Department of Medicine, University of Mississippi Medical Center, Jackson, MS

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Management of Hemodialysis Catheter Related Bacteremia (CRB) With an Adjunctive Antibiotic Lock Solution Zipporah Krishnasami, Donna Carlton, Lisa Bimbo, and Michael AIlon Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL

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Management of Hemodialysis Patients With Central Venous Stenoses or Occlusions Abigail FaIk, Jeffrey Guller, Scott Nowakowski, Harold A. Mitty, Victoria Teodorsecu, Joseph VassaIotti, and Jaime Uribarri Mount Sinai-New York University Medical Center, Departments of Radiology, Surgery, and Medicine, New York, NY

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New Empiric Expressions to Calculate spKT/V and eKT/V Alexander S. Goldfarb-Rumyantzev, Samuel Liu, and Michael Schwenk Hayward, CA

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Obese and Non-Obese Hemodialysis Patients Have a Similar Prevalence of Functioning Arteriovenous Fistula (AVF) Using Pre-Operative Vein Mapping Joseph Vassalotti, Abagail Falk, Victoria Teodorescu, and Jamie Uribarri Mount Sinai Medical Center, New York, NY

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Most Patients With Prosthetic Bridge Grafts (PBG) Are AV Fistula (AVF) Candidates Jeffrey J. Sands, Carlos E. Espada, Lori M. Ferrell, and J. Michael Lazarus Fresenius Medical Care, Winter Park, FL, and Lexington, MA

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Psychosocial Factors and Noncompliance in Hemodialysis (HI)) Patients (pts) Nabila Hussain, Joanna Q. Hudson, Saba Sile, Patricia Cowan, Naseeruddin Khan, and Sergio Acchiardo Nephrology, Ochsner Medical Institute, New Orleans, I.A, and the University of Tennessee, Memphis, TN

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Replacement of Cuffed Catheters Eliminates Epidural Abscess in Hemodialysis Patients With Bacteremia Kamal Amin, Mary Gellens, and Marie Philipneri St. Louis University School of Medicine, St. Louis, MO

TENTH ANNUAL CLINICAL NEPHROLOGY MEETING ABSTRACTS

51

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Safety and Efficacy of Tissue Plasminogen Activator (tPA) for Tunneled Catheter Clearance in an Outpatient Dialysis Unit Suresh Margassery and Mary Gellens St. Louis University, St. Louis, MO Safety in Repeat Exposure to Sodium Ferric Gluconate Complex (SFGC) in 1413 Patients Given by Slow IV Push Beckie Michael, Andrea Shaer, Steven Fishbane, and Jur Strobos Thomas Jefferson University, Philadelphia, PA, Medical University of South Carolina, Charleston, SC, Winthrop University Hospital, Mineola, NY,, and R&D Labs, Los Angeles, CA

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Serial Monitoring of New Arteriovenous Fistulas (AVFs) by Access Blood Flow (ABF) Measurements Sanjeev Suri, Susan Racjzak, and Brian M. Murray Renal Division, Erie Co. Medical Center, Buffalo, NY

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Successful Reduction of Anti-Hypertensives Using Bioimpedance Spectroscopy to Determine "Dry Weight" in Chronic Dialysis Patients Douglass T. Domoto and Marilyn E. WeindeI St. Louis, 310

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The Impact of Comorbidity on Vascular Access Related Events in Incident Hemodialysis Patients Nabeel Aslam, Renee Burr, Kelly DeVoogd, Michelle Shields, and Frank Bruns Renal & Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, PA

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The Use of Aspirin or Warfarin to Maintain Patency of Tunneled Hemodialysis Catheters C. L Obialo, A.C. Conner, and L.E Lebon Morehouse Dialysis and Morehouse School of Medicine, Atlanta, GA

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Use of the Lifesite® Hemodialysis Access System Reduces Risk of Vascular Access Infections John Moran Vasca, Inc., Tewksbury, MA

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Vancomycin Is the Preferred Antimicrobial Agent for Empiric Therapy in Hemodialysis-Related Infections Steven H. Ong, Karthik Ranganna, Jean Lee, Allan R. Tunkel, and Ziauddin Ahmed MCP Hahnemann University, Philadelphia, PA

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White Blood Cells and Mortality in Hemodialysis Patients Donald Reddan, Preston Klassen, Lynda Szczech, V~lliam Owen, and Edmund Lowrie Duke University, Durham, NC

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65% of Patients With Cuffed Catheters (CC) Have Adequate Vessels for AV Fistula (AVF) Creation Jeffrey J. Sands, Carlos E. Espada, Lori M. Ferrell, and J. Michael Lazarus Fresenius Medical Care NA, Winter Park, FL, and Lexington, MA

Hypertension 44

Accuracy of Blood Pressure (BP) Measurements in Hemodialysis (HD) Patients A. Kumar, M. Rahman, J.T. Wright, V. Griffin, M. Andrade, and M. C. Smith Case Western Reserve University, University Hospitals of Cleveland, and Centers for Dialysis Care, Cleveland, OH

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TENTH ANNUAL CLINICAL NEPHROLOGY MEETING ABSTRACTS

102

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Renovascular Hypertension and Ischemic Renal Atrophy Secondary to Fibromuscular Dysplasia in a Black Man: A Case Report Sameer Yaseen and Bradley Dixon University of Iowa, Department of Internal Medicine, Iowa City, IA The Dopamine D4 Receptor Knockout Mouse, Another Mouse With Hypertension Martin J. Bek, Shaopeng Zhen, Laureano D. Asico, David K. Grandy, Marcelo Rubinstein, Robert M. Carey, Gilbert M. Eisner, and Pedro A. Jose Georgetown University Medical Center, Department of Pediatrics, Washington, DC

Peritoneal Dialysis 61

Elderly Patients on PD Do Not Have a Higher Risk of Enteric Peritonitis Than Distinctly Younger Patients on PD Fadi Naj'ajgz Judith Bernardini, and Beth Piraino University of Pittsburgh, Pittsburgh, PA

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Nutritional Status and Lipid Profile in Uremic Patients Treated With CAPD Zerrin Bicikj Nurcan Yabanci, f21ver Derici, and Kadriye Altok Reis Gazi University Hospital, Nephrology Department, and Vocational Education Faculty, Nutrition Education Department, Ankara, Turkey

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Residual Renal Function (RRF) Is an Independent Predictor of Mortality in Peritoneal Dialysis (PD) Patients (pts) Bhavani Mahankali, Paul A. Fein, Krishnan Babu, Rajanna Sreedhara, Regina Lilly, and Morrell M. Avram Avram Center for Kidney Diseases, Avram Division of Nephrology, Long Island College Hospital, Brooklyn, NY

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Sevelamer HCL Improves Parathyroid Hormone (PTH) and Bone Function in Peritoneal Dialysis (PD) Patients with Probable Low Turnover Bone Disease Sharon Moe, Jan Peterson, Cindy Murphy, Erika Johnson, and Mark Deeg Indiana University and Roudebush VAMC, Indianapolis, IN

Progressive Renal Failure 98

An Association of Pre-End-Stage Renal Disease Epoetin Treatment with Post-ESRD Mortality Jay L. Xue, James Ebben, Wendy St. Peter, and Allan J. Collins Minneapolis Medical Research Foundation and University of Minnesota, Minneapolis, MN

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Development of Secondary Hyperparathyroidism (HPT) in Patients With Chronic Renal Insufficiency Nabila Hussain, Sergio Acchiardo, and Kim Huch Nephrology, Ochsner Medical Institute, New Orleans, LA, and University of Tennessee, Memphis, TN

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Erythropoietin Treatment of Anemia in Pre-End-Stage Renal Disease Patients by Physician Practice Jay L. Xue, James Ebben, Wendy St. Peter, and Allan J. Collins Minneapolis Medical Research Foundation and University of Minnesota, Minneapolis, MN

1 International Use of an Academic Nephrology Website Kevin C. Abbott, Thomas R. BoaI, David K. Oliver, Carl Boocks, Ronald K. Poropatich, Christina M. Yuan, and Paul G. Welch Nephrology Service and Telemedicine Directorate, Walter Reed Army Medical Center, Washington, DC

TENTH ANNUAL CLINICAL NEPHROLOGY MEETING ABSTRACTS

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Leptin, Growth Hormone and Lipid Status in Chronic Renal Failure in a Multiracial Population in the United Arab Emirates Enyioma Obineche, Michael Gillett, Abdishakur Abdulle, Mustapha Sulaiman, and Mona El-Rokhaimi Departments of Internal Medicine and Biochemistry, Faculty of Medicine, UAE University, Al Ain, Abu Dhabi, United Arab Emirates, and the Nephrology Unit, Public Services Department, Dubai, United Arab Emirates

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Novel Erythropoiesis Stimulating Protein (NESP) Administered Once Every Other Week Corrects Anemia in Patients With Chronic Renal Insufficiency (CRI) Michael Suranyi, Lynnae Jackson, John Lubina, and Anna McDermott-Vitak Liverpool Hospital, Sydney, Australia, and Amgen Inc., Thousand Oaks, CA

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Novel Erythropoiesis Stimulating Protein (NESP) Corrects Anemia in Patients With Chronic Renal Insufficiency (CRI) When Administered at a Reduced Dose Frequency Relative to Recombinant-Human Erythropoietin (rHuEPO) R. Walker, E Locatelli, J. Olivares, M. Wilkie, and the European/Australian NESP 980202 Study Group Melbourne, Australia, Lecco, Italy, Alicante, Spain, and Sheffield, UK

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Preliminary Results of the Prevalence of Anemia in Patients With Early Renal Insufficiency Study William McClellan Rollins School of Public Health, Emory University, Atlanta, GA

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Referral for Dialysis, Survival and Interface With Primary-Care Physicians Peter A. Rutherford and Jo Charles University of Wales College of Medicine and North Wales Health Authority, Wrexham, UK

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Renal Functional Reserve (RFR) in Pregnant and Non-Pregnant Women R~ Heguildn, A. Lapidus, C. Paz, O. Mulki, D. Bellusci, L. Voto, and A. Bernasconi Departments of Nephrology, Obstetrics, and Laboratory, Hospital Juan A. Ferndndez, Buenos Aires, Argentina

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The Impact of Early Education on Type of Vascular Access (VA) Placed in End-Stage Renal Disease (ESRD) Patients (pts) J.S. Lindberg, C. James, D. Scarlata, R. Sagastume, J. Nussbaum, M. Slowik, J. Best, M. Szerlip, J. Petitfils, J. Saviole, D. Jackson, D. Traina, A. Grant, E Husserl, and J. Copley Ochsner Medical Institution, New Orleans, LA, Amgen, Thousand Oaks, CA, and Baxter Healthcare, McGaw, IL

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The Incidence of Side Effects Associated With High Dose Ferric Gluconate (Ferrlecit TM ) in Patients With Severe Chronic Renal Failure (CRF) Behar Bastani, Anil Jain, and Gopal Pandurangan Division of Nephrology, St. Louis University School of Medicine, St. Louis, MO

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The Major Apoptotic Pathways in Chronic Cyclosporine Nephrotoxicity Are Regulated by Angiotensin II Ihab Wahba, William Bennett, and Takeshi Andoh Oregon Health Sciences University and Legacy Clinical Research, Portland, OR

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The Relative Utility of Urinary Total Protein and Albumin Dipstick Measurement in the Identification of Patients With Myleoma and Tubular Proteinuria James Profitt, Jane Wallace, Michael Pugia, David Newman, and Lucia D'Mello Bayer Corporation, Elkhart, IN, and the SW Thames Institute for Renal Research, St. Holier Hospital, Carshatton, Surrey, UK

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TENTH ANNUAL CLINICAL NEPHROLOGY MEETING ABSTRACTS

Transplantation 35

Acute Coronary Syndromes in Patients With End Stage Renal Disease Resulting From Diabetes After Renal Transplantation Compared With Patients on the Renal Transplant Waiting List Iman O. tlypolite, Jay Bucci, Christina M. Yuan, Allan Taylor, Paul Hshieh, David Cruess, Lawrence Y. Agodoa, and Kevin C. Abbott Office of Minority Health Research Coordination, National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, MD, Nephrology Service and Cardiology Service, Walther Reed Army Medical Center, Washington, DC, Uniformed Services University of the Health Sciences, Bethesda, MD, and Epidemiology and Biostatistics, USUHS, Bethesda, AID

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Effect of Adjuvant Mycophenolate Therapy on Rejection Response Rates in Corticosteroid-Treated African-American Renal Transplant Patients Eva M. Vasquez and Enrico Benedetti University of lllinois at Chicago, Chicago, IL

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Hospitalizations Resulting From Congestive Heart Failure in Patients With End Stage Renal Disease Resulting From Diabetes After Renal Transplantation Compared With Patients on the Renal Transplant Waiting List Iman O. Hvpolite, Jay Bucci, Christina M. Yuan, Allan Taylor, Paul Hshieh, David Cruess, Lawrence Y Agodoa, and Kevin C. Abbott Office of Minority Health Research Coordination, National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, MD, Nephrology Service and Cardiology Service, Walther Reed Army Medical Center, Washington, DC, Uniformed Services University of the Health Sciences, Bethesda, MD, and Epidemiology and Biostatistics, USUHS, Bethesda, MD

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Hospitalizations for Pulmonary Embolism After Renal Transplantation in the United States Daniel P. Tveit, Iman O. Hypolite, Ronald K. Poropatich, Paul Hshieh, David Cruess, Lawrence g Agodoa, and Kevin C. Abbott Walter Reed Army Medical Center, Washington, DC, and Uniformed Services University of the Health Sciences, Bethesda, MD

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Hospitalizations Resulting From Valvular Heart Disease in Patients With End Stage Renal Disease After Renal Transplantation Compared With Patients on the Renal Transplant Waiting List Iman O. Hypolite, Jay Bucci, Christina M. Yuan, Allan Taylor, Paul Hshieh, David Cruess, Lawrence Y Agodoa, and Kevin C. Abbott Office of Minority Health Research Coordination, National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, MD, NephroIogy Service and Cardiology Service, Walther Reed Army Medical Center, Washington, DC, Uniformed Services University of the Health Sciences, Bethesda, MD, and EpidemioIogy and Biostatistics, USUHS, Bethesda, MD

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Impact of Antihypertensive Treatment on Parathyroid Hormone in Kidney Transplant Recipients Viola Kobelt, Barbara Suwelack, Uta Hillebrandt, Ulf Gerhardt, and Helge Hohage Medizinische Poliklinik, University of Muenster, Muenster, Germany

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Long Term Cyclosporine Kinetiks and Its Influence on Lipid Status in Renal Transplant Recipients EK. Matzkies, W. Keuthage, U. Gerhardt, B. Suwelack, and H. Hohage University of Muenster, Medical Department, Muenster, Germany

86 Long-Term Effects of ACE-Inhibitors and/3-Blockers on Blood Pressure and Kidney Function in Renal Transplant Recipients Barbara Suwelack, Viola Kobelt, Matthias Erfmann, Ulf Gerhardt, and Helge Hohage Medizinische Poliklinik, University of Muenster, Muenster, Germany

TENTH ANNUAL CLINICAL NEPHROLOGY MEETING ABSTRACTS

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Malignant Nephrosclerosis as a Complication of Pediatric "En Bloc" Renal Transplantation Abinash Roy, Reginald Y Gohh, Paul E. Morrissey, and Lance D. Dworkin Department of Medicine, Division of Nephrology, Brown University School of Medicine, Providence, RI

27

Manipulating the Co-Stimulatory Properties of Antigen Presenting Cells: A Key Strategy for the Promotion of Immunologic Tolerance Matthew D. Griffin, Lori A. Bachman, David J. McKean, Rajiv Kumar, and Jeffrey A. Bluestone Department of Internal Medicine and Department of Immunology, Mayo Foundation, Rochester, MN, and UCSF Diabetes Center, University of California, San Francisco, CA

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Pamidronate (PAM) Therapy for Bone Loss (BL) After Heart (HTX) or Kidney Transplantation (KTX) Jack AvanelIe, Jill Lindberg, Katherine R. Tuttle, Lynn R. Dahlstrom, Truman E. Cantrell, Robert A. Short, Donald Sherrard, John B. CopIey, and Catherine Staffeld Ochsner Clinic, New Orleans, LA, The Heart Institute of Spokane, Spokane, WA, and the University of Washington School of Medicine, Seattle, WA

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Plasmapheresis in Posttransplant Recurrence of Focal Segmental Glomerulonephritis in Adults--Decline in Proteinuria Predicts Outcome Abinash C. Roy, Reginald Y Gohh, and Paul E. Morrissey Department of Medicine, Division of Nephrology, Brown University School of Medicine, Providence, R!

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Pregnancy in Renal Allograft Recipients A.R. Bernasconi, A.M. Lapidus, L. Voto, A. Gerszten, and R.M. Heguildn Department of Nephrology and Department of Obstetrics, Hospital Juan A. Ferndndez, Buenos Aires, Argentina

87

Randomized Study on the Conversion of Treatment With Calcineurin Inhibitors to Mycophenolate Mofetil in Chronic Renal Graft Failure B. Suwelack, U. Gerhardt, K.H. Rahn, and H. Hohage Medizinische Poliklinik der Universitaet Muenster, Muenster, Germany

28

Renal Transplantation Following Bone Marrow Transplantation From the Same and Different Donor Survival Rate and Need for lmmunosuppresion Khaled Hamawi and John A. Bertolatus Department of Medicine, University of Iowa, Iowa City, IA

60

The THI,erH2 Paradigm Revisited: Regulatory Functions ofAltoreactive TH2 Clones In Vivo N. Najafian, M.H. Sayegh, and A.M. Waaga Renal Division, Brigham and Womens Hospital, Boston, MA

Other 7

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Amphibian Proximal Tubule Cells Contain CFTR C1- Channels in the Basolateral Membrane Srisaila Basavappa and Emile L. Boulpaep Yale University School of Medicine, Department of Cellular and Molecular Physiology, New Haven, CT Basolateral CO2 Induces Intracellular Calcium Rise in the Rabbit $2 Renal Proximal TuNe P_atrice Bouyer, Yuehan Zhou, and Walter E Boron Department of Cellular and Molecular Physiology, Yale University, New Haven, CT

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TENTH ANNUAL CLINICAL NEPHROLOGY MEETING ABSTRACTS

Comparative Resource Use for Erthropoietin (EPO) Users and Non-Users During Pre-Dialysis Roger London, George A. Goldberg, and Sally Wade Oxford Health Plans, Trumbull, CT, and Protocare Sciences, Santa Monica, CA

68 Effect of Phosphate Binders on Supplemental Iron Absorption in Healthy Subjects M.C. Pruchnicki_hJ.D. Coyle, and W.H. Bay Ohio State University, Columbus, OH 21

Modulation of Vasopressin-V2 Receptor Signaling and Adenylyl Cyclase VI With Chronic Vasopressin Exposure in Rat Kidney Carolyn A. Ecelbarger, Crystal A. Bickel, and Joseph G. Verbalis Division of Endocrinology and Metabolism, Department of Medicine, Georgetown University, Washington, DC

79

NAT2 and NQ01 Variants and Risk for RCC Jan C. Semenza. A. Ziogas, J. Largent, D. Peel, and H. Anton-Culver School of Community Health, Portland State University, Portland, OR, and Epidemiology Division, University of California, Irvine, CA

18 Reducing Hyperparathyroidism in African-American Hemodialysis Patients Using Paricalcitol P. Crawford, M. Sobrero, S. Short, A. Deering, and T. Young FMC Neomedica, Evergreen Park, IL 47

Resource Utilization Pattern of Patients During Pre-Dialysis Roger London, George A. Goldberg, Amy Solis, and Sally Wade Oxford Health Plans, Trumbull, CT, and Protocare Sciences, Santa Monica, CA

29

Role of Phospholipase A2S in Hydrogen Peroxide-Induced Arachidonic Acid Release in Murine Mesangial Cell Won K. Han, Adam Sapirstein, and Joseph V. Bonventre Massachusetts General Hospital and Departments of Medicine and Anesthesia, Harvard Medical School, Charlestown, MA

66

Studies of the Juxtaglomerular Apparatus (JGA) Using Two-Photon Fluorescence Microscopy Janos Peti-Peterdi Shigeru Morishima, Yasunobu Okada, and P. Darwin Bell University of Alabama at Birmingham, Birmingham, AL, and National Institute for Physiological Sciences, Okazaki, Japan

82

The Activities of the Janus Kinase-Signal Transduction and Activator of Transcription (Jak-STAT) Pathway and the Extracellular-Regulated Protein Kinase (ERK) Pathway Determine IFN-Response in Renal Cancer Cells Mark M. Song and Jae Wi UCLA School of Medicine, Los Angeles, CA

93

Transcriptional Activity of the Human SMAD7 Promoter Depends on Cooperative Interactions Between AP-1, E-box and SMAD Transcription Factor Binding Sites G. yon Gersdorffi, E Rezvani, and E. Bottinger Division of Nephrology, Albert Einstein College of Medicine, Bronx, NY

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Urinalysis Strip Results Obtained by Untrained Volunteers: Protein, Creatinine and P:C Ratios Jane E Wallace, Todd C. Cast, Michael J. Pugia, and Donald R. Parker Bayer Corporation, Elkhart, IN