The curative effect of mallein in glanders

The curative effect of mallein in glanders

ABSTRACTS AND REPORTS. diffuse pneumonia; inflammation of the tendon sheaths and loss of the hoof were more common among them than among the German h...

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diffuse pneumonia; inflammation of the tendon sheaths and loss of the hoof were more common among them than among the German horses. The Austrian horses had steel shoes, the German horses iron shoes; both stood the journey well. The long distance ride showed that the sole ought to be well protected by the shoe, and that a little more horn than usual ought to be left on the sole in order to prevent accidental bruising.-Berliner Thieriirztliche Wochenschrift.

CONCOMITANT OUTBREAKS OF HUMAN AND AVIAN DIPHTHERIA. DEBRIE briefly reports the clinical history of 6 cases of diphtheria which occurred in the garrison of Sebdou, and states that while the sixth case (two were fatal) was still under treatment in hospital 10 fowls kept in a house not far from the hospital were attacked with diphtheria, and exhibited symptoms strikingly like those present in the human beings. Five of the 10 fowls died, and two heads were sent to Arloing, who confirmed the diagnosis of fowl diphtheria. The fowls had been fed by a hospital attendant, and It was ascertained that an iqentical outbreak had occurred among the fowls at a neighbouring place, from which one of the 6 cases of human diphtheria had been brought. The author is not disposed to admit, notwithstanding the difference between their causal microbes, that there was no relationship between the outbreaks of diphtheria among human beings and fowls, but inclines to the view that human dIphtheria is transmissible to fowls, and vice versa.- Centralblatt fiir Bakteriologie und Parasitellkunde.

THE CURATIVE EFFECT OF MALLEIN IN GLANDERS. IN Febtuary last Professor Pilavios of Athens sent to the French Academy of Medicine a report regarding the use of mallein in the treatment of glanders. He has been pursuing his investigations since, and he now reports that both he and his colleagues have been struck with astonishment at the success of the mallein treatment. Horses suspected of glanders have been completely cured by repeated injections of l1Iallein at intervals of eIght days. In all eight horses have been thus treated, and all these animals came from regiments in which glanders had prevailed for years. Before injection the horses showed all the clinical symptoms of glanders, and had on that account been isolated. They reacted to the first two injections in the ordinary way, but at the third and each succeeding injection (with large doses) they behaved in this respect like healthy horses, and exhibited no reaction. Immediately after the third injection the symptoms of glanders began to abate, and after 40-45 days they had completely disappeared. After other 35 days the horses were again injected with mallein, but not the slightest reaction followed. At the date of the report the horses 'were doing their work as well or even better than other sound horses. The mallein treatment has been found successful only in the early stages of glanders; in the advanced stages of the disease the injection of mallein may hasten death. In some of the latter cases the horses died with the symptoms of peracute nasal glanders 3 or 4 days after the first injection.-, Berliner Thierdrztliche Wochenscllrift.